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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9f248a57bfc4e938c91b6f6989410e78db91f84e618e082c95f441a6f1f3085' 
  AND token = 'C4H0i7Lyt+LJ4QbfdnTrmWs8DFnqlGVdo5RVPQZ35Gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}