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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df2244939347255d6ff6227361961c5143ef57dde3fa2599cd2d8c408664ca0' 
  AND token = 'SpF2f5El+0zQuRjFvPiTxpFcx6x+wfQRQdXZWEX1h1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}