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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1edc3fd95b294c05e7d98555e230db946818d4e1e416fcbabed7d23edf339be2' 
  AND token = 'rBucFbtM61+boiWYIVsi0tP7wKVDE3ct/r8YOLyWBi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}