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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a6b312a4076c5efbe4b8f96eedb4fcf09130aa76ce73d9748f00677d8aa906b' 
  AND token = 'iuopchOFygfUBIRyUvdcO4w+CgIHXoLZM8pQByP9L2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}