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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '819b1f5c7ec4c91b3ce11f645b27077c5592883b9d1b292b7b2119a4fe48e73a' 
  AND token = 'p2R/88mWD23FgKMl5Xav0n4OsqFlgieClKIUelSR4DQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}