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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4de09ad6153ce07f48bffaa4c74a7b452c7ee60349c99086cf8d9df4de344835' 
  AND token = 'iNc2JXsV13NeFp2WMtxYdW3yAtRJvQdLM6xHhnflGGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}