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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2b24e487ff8e9919c88b22ab4b3e4a79e9a215ec5ee8f933bae291041efd063' 
  AND token = '3+M9/dDUO4Cx4b5TjlALPnkXVVRoqfKKl7yFSEgoOfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}