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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28d65cc6fba805008f772119e85d0e4b3d69d5f4952d220fe909de34cc454b39' 
  AND token = 'pU8GcZFrifFFtxEkctX4EyXYKjoMw16RQaKlEW7b0LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}