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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b79170a3c8e5227dfb5e2061be1560d76d14940cfd71ed3cac594e055edc511' 
  AND token = 'quZGFVA50OTnmVjd3DdXfQAHkmelfM1s+R4mDWiZ6j8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}