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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b2ea16aa9026a04ec4a1d59de709a17fb6075f48e99497daffa520fc33e6f99' 
  AND token = '3wkc8DjIJWgymftNLn6e/euFfduiz//9ZnEghH1paPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}