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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '371d1cbac55f6aadbdaef1002527e540dff364d31659ad15d9c61801e45600b0' 
  AND token = 'VrVVay/0nVBKA+70P4j7BjKpmMCKAEq1shpVr4jRsdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}