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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443c5a711af67998b72a85939c045d2fa84466e3129088f6a054879c8f323d3c' 
  AND token = 'zwKdHTsCh0pA5PNDc/eBDZuVN98N3iyLBjE1p6U6snc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}