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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c64743f93124b6d206ec3d771d021fa24fa2c1e19bc2b03136d924a80526b4a' 
  AND token = 'ntev+C747IdtW3jpvU/RETJg3wh9/lY4tigfSN6jv4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}