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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5e63f649a13477f263375e6f1d3fee3a3d64243c86b36ae49d9aa79386ebbd9' 
  AND token = 'GhGC9D6pOdG7RR4PfF01b1rcDPAux74rKKKzStDlgCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}