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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddff02c03dd20e812455e86686662ce857b6aaed2f4695ff11f1b4f34c3941b1' 
  AND token = 'MFIsIoJU3LjuIuus5Tqr3qVu0uK40gfKt9jAOuzBfG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}