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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6ad377a17a6698f320e0c170e471012a385486f916f76a404d042226332b50b' 
  AND token = 'vbVqzzlnX2TOsZ9s/eG734NC3Ugdl8AHyRzQI5lGEqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}