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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b17906e2a7b1b120b31644d65e753af3d87a4ceb166b890f413049268c8d0a64' 
  AND token = 'NQqDZCMkytlM0BmHtO6L9A0Z3yuEtt1A/jbjz0tWtSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}