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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535b488da07339b7ead1f77ff909f8e4369f9581b2b43296a3cd8cbe15ba7b4a' 
  AND token = '7yuugbV9CLMV4EHqJDhJrOkX01j8qu8mkEqqOYdDqJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}