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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11a010c4ec7bd3a74e9d4fd070496a5d642db8a704dbcaf6b4dddbb7c602a473' 
  AND token = 'D4Y+DsqzcRa6EtTvrq64Uyqrr9QnL3rQUDHWyYujUl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}