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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5ee4d798fcb625923a5e4161c35030370064a779a6875eb2036d0d48cf6bae6' 
  AND token = 'TCZGHZFfkYB/Bt+Ys60Flun9cuU0pUOvm5Ky4TFZwuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}