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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8102c2be566c8c324e7cbc4a698a7ab81a605547d297d9d672e0a12f33332fb5' 
  AND token = 'zBeMQtuDMGn2e3kdRu+1LSJIYYf51vRfX+Nzjw4nG44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}