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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dd84006a8d3a200558a7432cc35f144a1b19e0b0e93298cd3c6b91ca3188f7e' 
  AND token = 'FGOutgBCtbTWepyhSUzNiZ2ErplhkiGSO3N9N6nj8bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}