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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31481647b1bf2f072cfefd4c02a29f0d465fe9cdbe923cdfdd153f7211b59d21' 
  AND token = 'QUiyw7yU349PQOjcM+OB8OQJpnnQAKBQrsu9lqTv8NI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}