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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb66fd2a162686b9c1db7c5de979a46f2de674f8dc69366faf7473d6e076ae1f' 
  AND token = 'Yyv2XoxJcc7S4MB0llXaahgKgVnrJlZ9LnkBrxGGg/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}