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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db4afd3226778f90f96eae4eaea26dc8d75037760be1e9c464b0deea1c081482' 
  AND token = '45Hm+Hg3Fkr1fO9zMHmFil7z3i5ge7pcAjrC0SkRhc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}