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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d9bcc8eec40d323d39c758456326162e1122855b0626e6c1276315c9f7486c4' 
  AND token = 't2wLyurtFfPua+0QS93OMPp2rNDgomLfGFTm4cMn9lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}