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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66153e31e31ad5b7c5843d714efa325a961a700749eb56a3130d441fd86a4c3a' 
  AND token = 'AzEalYJ1fke/5I614Y1qHucfp90iBwuvMG2PHcjxtQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}