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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f1f77196633f03a5d67ce1d381727c31c1b4e8d3f62df55d1e12cac7ce6c055' 
  AND token = 'LDVihAaq2DriOUMxqkuGL7zRFbzNCD0v1DZzPzhR2hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}