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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b2bf650d161cf942f4e09e17c51959f7ad1d4020393cf9fe71a490d20145e3a' 
  AND token = 'WeC3bOd0/y5/baPR3ZB4KSojASeXNoJ/rC/1v+lFmfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}