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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c786126fb71de4b612a977b3d1d3b2d73db2c9c1d0c25c9f9809a0125fc19799' 
  AND token = 'AHlxxLKDGAre/3aM4+wpbqfBhN2xFeF4zkbu9DTQtWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}