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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26a4f53cd05c9ebf49fae1d18def212c75c847e7ed5ebe29c6ebb6dee9769a19' 
  AND token = 'Fk1NY00F17Xf6QOWhlKcUklqJJ6xHYagAFGHX+3pKSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}