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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a275a3b5c35b53e7616c5158af7303bb1faae14abbf3f906c76572f88c856c76' 
  AND token = 'esiiRBSPb5oKJ2OhjTI3tSbYThN8uITSxjeA8Wr8/zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}