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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45518370460d0968106f252d2be2ead6705dcb8a24aa82f24266f93f3461f46d' 
  AND token = 'TgxX/5Ykpz5+Gud+CFrXPEU7itICxsai1mhyF+AAVKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}