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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '108e081ffcb8710860aae98e4268c71aa1357034359f4533e24c1ab19163ee65' 
  AND token = 'aTlE3OoQfkOxsucNSB4bMcv9OTaLDnKV1nhB5Bd8KIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}