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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe599e58ee63e7003f0899db00ebb50fa6f2036090e03226007dfbae05ca1c20' 
  AND token = 'HK1pMM2SPdKH4COMn5RMfOx4J2PJs2rwbLil3gJFwIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}