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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6656d2a340c5f823bdfa9939207cc254f8c228d6eefe3fc2a8577f4f4da21f18' 
  AND token = 'nPV6srX6MVz+pMo8Ir5OdwHtYQLlS8FLv2dIAY/lYJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}