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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad0c59a015b78df693614bda5c59fdc89ed8d838a1848d26f93c8f0efb88e53' 
  AND token = 'xSr4mI59+HjHMGEGr79/vkiLIH/kzR9IDjGIsbnOOG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}