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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f92d8e4149a070cbc317baa79b2891956c5f739dec28bbd54c0729e245e80cc5' 
  AND token = 'yGCKpr/R1mXN9zWz5BUFw88on+nLj7VAoPQdd4EtUZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}