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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bb89a068e7adbf76130aef3ed21b2088b0a137e2e5b6b7ee1004644137c8699' 
  AND token = '7GwTpnRrjfBgiFlfOJRI5XvNA3pom0ovgUTdoeUwrXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}