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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '157b50bfe0510cbd53b512d9943ef96d7c0cf99495267bda98407e10a7a43ef6' 
  AND token = 'u34fg8zRqbMMzQVNsWvT0rsNVUwOXHJhw2TNZ16kSdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}