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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74ff0d16118d3aa8a0ddc232c2d76d2397d31b91d2d9a11f7dd980441f183a1b' 
  AND token = 'C/nACGpv/YOfMPcorPmAy16XHx9+250h/AmUE0PRQO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}