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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2818f326c8df9daf61a1f520702be20eed07134902cefd69152d7d1b172a8b84' 
  AND token = 'DIYtYt89XIm1F5u3BpYFERAx994i3yy++X1D/oWcJc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}