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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef78b9735fe0a032236689b0dc28b2cfde3784d1f6f79b6c4df606a67f579a7b' 
  AND token = 'x407vpIQU++8E5d7xFDX7c/kDBNWK01VxrpfCvxPNAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}