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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17a6b2e1ebf7409c8d5e66b109608ada2606019131435d73a5bb2735c4da42b4' 
  AND token = 'xaQqeF5icSpCtlWpFJO/Rv2ijxuFf+MUAERZOScexq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}