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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4f18168e51f54f684fca95f9b4f8377d6a2d30ca327fb87a462e713b8dfd1fc' 
  AND token = 'sePIbgsZarrltZmss7yblgzpyb5H4cs+hYyoQqlTSSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}