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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad18e8092f3210c23b7cd2e61da157d629399ef8c4245e7c187ff88e95ac1a52' 
  AND token = 'Jc1kDnpwLdPc793yTPV462d9w6W//0Tc356ivXowlZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}