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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '551151522ef81a7c5b75938ee4004d81d7ccf4afc9f21dbeb18e551c02165af4' 
  AND token = 'ApaApLciCPBG0U5U2ql6cG4xDai4qQF/5206jl253GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}