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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f059f42ee2471a2cbf587b828fd0a2f4df83d0283765114f506e7a8b6a2c680' 
  AND token = 'sD286qfmgWVDdiJtW+qTWNbOVITM7FjLHQuw+uT2lPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}