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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fd58b4dfe4b3d0e135a637f2ad88dd0b33646e19863768ef3cdcda997b96edf' 
  AND token = 'NJ+QpZLyBBhWeYMHgO10X1bEupIOHqhQGOaQ9xoC7Gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}