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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11a37cf7ba1dfe86077e3e71be50d650c5362db4b047e5a585705d0fdc234b8b' 
  AND token = 'it7nAN/g/Vn4bZRhbUkcO76LEiXdc5iWOaDFvoT4iFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}